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Post-exposure treatment of Ebola virus using passive immunotherapy: proposal for a new strategy J. Venom. Anim. Toxins incl. Trop. Dis.
Chippaux,Jean-Philippe; Boyer,Leslie V; Alagón,Alejandro.
Background Better treatments are urgently needed for the management of Ebola virus epidemics in Equatorial Africa. Methods We conducted a systematic review of the literature on the use of passive immunotherapy for the treatment or prevention of Ebola virus disease. We placed findings from this review into the context of passive immunotherapy currently used for venom-induced disease, and recent improvements in manufacturing of polyvalent antivenom products. Results Passive immunotherapy appears to be one of the most promising specific treatments for Ebola. However, its potential has been incompletely evaluated, considering the overall experience and recent improvement of immunotherapy. Development and use of heterologous serum derivatives could protect...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Ebola; Epidemics; Immunotherapy; Prophylaxis; Africa.
Ano: 2015 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1678-91992015000100203
Registros recuperados: 1
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